Clinical characteristics of the severe allergic asthma phenotype.

Think allergy

Over 50% of severe asthma patients have an allergic component.1

Allergic asthma is an easily recognised asthma phenotype,2 and patients with this condition may have:

Personal history of allergic comorbidities
High or low eosinophil levels
Serum levels of allergen-specific IgE² ⁴
Symptoms and/or exacerbations in response to allergen exposure⁴
A positive skin prick test² ⁴
Family history of allergic disease² ⁴

IgE, immunoglobulin E; SAA, severe allergic asthma.


  1. Hamelmann E. Eur Respir Rev 2007;16(104):61–66.
  2. Global Initiative for Asthma: Global Strategy for Asthma Management and Prevention. Available at: [Accessed July 2022].
  3. Humbert M et al. Eur Respir J 2018;51(5):1702523.
  4. Haselkorn T et al. Asthma 2006;43(10):745–752.
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UK | August 2022 | 225869

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