Fatigue is one of the most bothersome PV symptoms for many patients and may interfere with their daily life.1 Play the video below to discover one patient’s experience of PV-related fatigue.


Living with PV can feel isolating for patients. Play the video below to hear one patient’s advice to others living with PV.


The global MPN Landmark survey recruited 223 patients living with PV across different continents.The most common symptoms experienced in the past 12 months were fatigue or tiredness and pruritus.1

The figure '72%'

of patients with PV experienced a reduction in quality of life due to MPN symptoms1

Fatigue or tiredness and weakness were reported as the most severe symptoms, with 84% of patients with PV saying fatigue is the symptom they would most like resolved.1


PV impacts patients overall ability to work1

Icon of a sofa.
 The figure '40%'

Activity impairment

Icon of a lightbulb with a no entry sign.
the figure '33%'

Work impairment


Leukaemia Care, MPN Voice, Macmillan and Blood Cancer UK are examples of patient advocacy groups (PAGs).

They represent patients and carers, providing them with credible information as well as support.


Macmillan Cancer Support logo.

Macmillan Cancer Support helps patients navigate the emotional, practical, physical and financial impact cancer can have on their lives. They help guide patients through every stage of their cancer journey and do whatever it takes to support people living with cancer. They also host an online community so that patients can talk to other people going through a similar experience.

Find out more about Macmillan Cancer Support www.macmillan.org.uk

Leukaemia Care logo.

Leukaemia Care is dedicated to ensuring that everyone affected by blood cancer receives the best possible diagnosis, information, advice, treatment and support. They provide information, advice and support to improve the lives of people affected by leukaemia, MDS and MPN.

Find out more about Leukaemia Care www.leukaemiacare.org.uk


 Blood Cancer UK logo.

Blood Cancer UK’s vision is to beat blood cancer by funding research and supporting those affected. They provide support and information for people living with any kind of blood cancer.

Find out more about Blood Cancer UK www.bloodcancer.org.uk

MPN Voice logo.

MPN Voice provides clear and accurate information and emotional support to anyone living with an MPN, as well as their friends and families. They offer patient forums and peer-to-peer support so that patients know they are not alone and can talk to someone else living with an MPN.

Find out more about MPN Voice www.mpnvoice.org.uk


Understanding MPNs – download here

A guide to help patients and caregivers understand their MPN and how it may affect them.


Hydroxyurea is synonymous with/refers to hydroxycarbamide throughout.

HU, hydroxyurea; MDS, myelodysplastic syndromes; MPN, myeloproliferative neoplasm; PAG, patient advocacy group; PV, polycythaemia vera.


  1. Harrison CN, et al. Ann Hematol. 2017;96:1653–1665.
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UK | July 2023 | 253141

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