Burden of disease

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The burden of chronic urticaria.

In one study, compared with other skin conditions, chronic urticaria was reported to have the second highest impact on quality of life, even higher than psoriasis.¹

The impact of chronic urticaria on daily life is often underestimated.^2,3 Chronic urticaria can have a substantial effect on a patient’s physical, emotional, social and economic well being.

Patients who experience problems with:^4,5

Common and debilitating effects of angioedema:^6–8

The healthcare burden of chronic urticaria

The long wait experienced by many patients before diagnosis and/or appropriate referral also contributes to the healthcare burden of chronic urticaria.^4,6

• Mean diagnostic delay: 4 years^‡6
• Average trips to GP before diagnosis: 13^‡6
• Patients presenting as an emergency at least once: 49%^‡6

*Self-reported data from 673 patients with CSU in Canada, France, Germany, Italy, Spain, Netherlands and UK whose symptoms persisted for ≥12 months despite treatment.^4
†Self-reported data from 769 patients with chronic urticaria (hives lasting for >6 weeks) in France, Germany, Italy, Spain and UK.^5
‡75 patients with CSU.⁶

CSU, chronic spontaneous urticaria; GP, general practitioner.

References

1. Zuberbier T, et al. Expert Rev Clin Immunol 2015;11(2):171–180.
2. Kang MJ, et al. Ann Dermatol 2009;21(3):226–229.
3. Silvares MR, et al. Rev Assoc Med Bras (1992) 2011;57(5):577–582.
4. Maurer M, et al. Allergy 2017;72(12):2005–2020.
5. Balp MM, et al. J Eur Acad Dermatol Venereol 2018;32(2):282–290.
6. Mistry A. Chronic Spontaneous Urticaria: impact of the diagnostic delay on healthcare resources. The British Society for Allergy & Clinical Immunology (BSACI) annual meeting. Telford International Centre, UK. September 2015.
7. Ferrer M, et al. Eur J Dermatol 2017;27(5):455–463.
8. Staubach P, et al. Allergy 2018; 73(3):576–584.