Prescribing information

 

Prescribing information

Cosentyx, alone or in combination with methotrexate (MTX), is indicated for the treatment of active psoriatic arthritis (PsA) in adult patients when the response to previous disease-modifying anti-rheumatic drug therapy has been inadequate; active ankylosing spondylitis (AS) in adults who have responded inadequately to conventional therapy; active non-radiographic axial spondyloarthritis (nr-axSpA) with objective signs of inflammation as indicated by elevated C-reactive protein and/or magnetic resonance imaging evidence in adults who have responded inadequately to non-steroidal anti-inflammatory drugs; active enthesitis-related arthritis (ERA) in patients 6 years and older (alone or in combination with MTX) whose disease has responded inadequately to, or who cannot tolerate conventional therapy; active juvenile psoriatic arthritis (JPsA) in patients 6 years or older (alone or in combination with MTX) whose disease has responded inadequately to, or who cannot tolerate, conventional therapy.1,2

Full indication for Cosentyx can be found here


What might Cosentyx deliver for your eligible patients?

Tick icon with the text ‘Efficacy across the key manifestations of PsA’.
Tick icon with the text ‘Efficacy across the hallmarks of axSpA’.
Tick icon with the text ‘Efficacy in JIA’
Infographic. 1,000,000 patients treated worldwide.

patients treated globally, and counting, across all indicatons*3

Icon of a clipboard. Across 100+ clinical trials.

100+ clinical trials†4

Icon of a calendar. 8 years of real-world experience.

8 years of real-world experience*5–7

Icon of a tick and a circling arrow. 8 indications.

8 indications1,2

Cosentyx is intended for use under the guidance and supervision of a physician experienced in the diagnosis and treatment of conditions for which Cosentyx is indicated.  Please refer to the Cosentyx SmPC for full product information before prescribing.1,2

 

Therapeutic Indications1,2

Cosentyx is indicated for the treatment of moderate to severe plaque psoriasis (PsO) in adults, children and adolescents from the age of 6 years who are candidates for systemic therapy; active psoriatic arthritis (PsA) in adult patients (alone or in combination with methotrexate [MTX]) when the response to previous disease-modifying anti-rheumatic drug therapy has been inadequate; active ankylosing spondylitis (AS) in adults who have responded inadequately to conventional therapy; active nonradiographic axial spondyloarthritis (nr-axSpA) with objective signs of inflammation as indicated by elevated C-reactive protein and/or magnetic resonance imaging evidence in adults who have responded inadequately to non-steroidal anti-inflammatory drugs; active moderate to severe hidradenitis suppurativa (HS; acne inversa) in adults with an inadequate response to conventional systemic HS therapy; active enthesitis-related arthritis (ERA) in patients 6 years and older (alone or in combination with MTX) whose disease has responded inadequately to, or who cannot tolerate, conventional therapy; active juvenile psoriatic arthritis (JPsA) in patients 6 years and older (alone or in combination with MTX) whose disease has responded inadequately to, or who cannot tolerate, conventional therapy.1,2

*Worldwide, across all licensed indications.
Not limited to licensed indications. Refer to the Cosentyx SmPC for full prescribing information.1,2

AS, ankylosing spondylitis; axSpA, axial spondyloarthritis; CRP, C-reactive protein; DMARD, disease modifying anti-rheumatic drug; ERA; enthesitis-related arthritis; HS, hidradenitis suppurativa; JIA, juvenile idiopathic arthritis; JPsA, juvenile psoriatic arthritis; MRI, magnetic resonance imaging; MTX, methotrexate; nr-axSpA, non-radiographic axial spondyloarthritis; NSAID, non-steroidal anti-inflammatory drug; PsA, psoriatic arthritis; PsO, plaque psoriasis; SmPC, Summary of Product Characteristics.

References:

  1. Cosentyx® (secukinumab) GB Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/3669/smpc [Accessed December 2023].
  2. Cosentyx® (secukinumab) NI Summary of Product Characteristics. Available at: https://www.emcmedicines.com/en-gb/northernireland/medicine?id=ecdc7f05-... [Accessed December 2023].
  3. Novartis Data on File. Secukinumab (Sec008). February 2023.
  4. Novartis Data on File. Rheumatology UK 246.
  5. European Medicines Agency. European public assessment report. Medicine overview. Cosentyx (secukinumab).
  6. Gottlieb AB, et al. Act Derm Venereol 2022;102:adv00698.
  7. Melgosa Ramos FJ, et al. JEADV Clin Pract 2023;1–7. DOI:10.1002/jvc2.185.
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UK | December 2023 | 298718

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Novartis via [email protected] or online through the pharmacovigilance intake (PVI) tool at www.novartis.com/report
If you have a question about the product, please contact Medical Information on 01276 698370 or by email at [email protected]