This site contains information for healthcare professionals on Xolair for severe allergic asthma.
___________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
Xolair should only be considered for patients with convincing IgE (immunoglobulin E) mediated asthma.1
Adults and adolescents (12 years of age and older)
Xolair is indicated as add-on therapy to improve asthma control in patients with severe persistent allergic asthma who have a positive skin test or in vitro reactivity to a perennial aeroallergen and who have reduced lung function (FEV1 <80%) as well as frequent daytime symptoms or night-time awakenings and who have had multiple documented severe asthma exacerbations despite daily high-dose inhaled corticosteroids, plus a long-acting inhaled beta2-agonist.1
Children (6 to <12 years of age)
Xolair is indicated as add-on therapy to improve asthma control in patients with severe persistent allergic asthma who have a positive skin test or in vitro reactivity to a perennial aeroallergen and frequent daytime symptoms or night-time awakenings and who have had multiple documented severe asthma exacerbations despite daily high-dose inhaled corticosteroids, plus a long-acting inhaled beta2-agonist.1
*Xolair provides clinically meaningful improvements in quality of life for patients with severe allergic asthma.2
FEV1, forced expiratory volume in 1 second; IgE, immunoglobulin E; SAA, severe allergic asthma.
References
- Xolair® (omalizumab) Summary of Product Characteristics.
- Braunstahl GJ et al. Resp Med 2013;107(8):1141–1151.