Prescribing information



Durable relapse-free survival at five years1,2

TAFINLAR (dabrafenib) in combination with MEKINIST (trametinib) is indicated in adults for the adjuvant treatment of Stage III BRAF V600-positive melanoma, following complete resection.3,4

Landmark data demonstrate that the combination of TAFINLAR + MEKINIST offers patients a chance for DURABLE relapse-free survival at five years1,2

Please select an option below to find out more about the efficacy and safety profile of TAFINLAR + MEKINIST from the Phase III COMBI-AD clinical trial, or to discover more about patient management.


  1. Long GV, et al. N Engl J Med 2017;377:1813–1823.
  2. Dummer R, et al. N Engl J Med 2020;DOI:10.1056/NEJMoa2005493.
  3. TAFINLAR (dabrafenib) Summary of Product Characteristics.
  4. MEKINIST (trametinib) Summary of Product Characteristics.
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UK | December 2020 | 100874

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Adverse events should be reported. Reporting forms and information can be found at Adverse events should also be reported to Novartis via [email protected] or online through the pharmacovigilance intake (PVI) tool at
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