FOR WOMEN WITH ADVANCED BREAST CANCER, TIME IS PRECIOUS

KISQALI is indicated for the treatment of women with hormone receptor (HR)−positive, human epidermal growth factor receptor 2 (HER2)−negative locally advanced or metastatic breast cancer in combination with an aromatase inhibitor or fulvestrant as initial endocrine-based therapy, or in women who have received prior endocrine therapy.* In pre- or perimenopausal women, the endocrine therapy should be combined with a luteinising hormone-releasing hormone (LHRH) agonist.1

* KISQALI is not recommended to be used in combination with tamoxifen.1

 

With KISQALI + ET,* you can give your HR+/HER2− aBC patients more time

worth having1–9

 

More time with their loved ones

  • KISQALI + NSAI + LHRH agonist is the only CDK4/6 inhibitor that offers statistically significant longer OS than placebo +NSAI + LHRH agonist for premenopausal women with HR+/HER2− aBC4,10,11
  • KISQALI + ET* is the only CDK4/6i to show statistically significant improvements in OS in two phase III trials1–4,12
 

The quality time they need

Improved or preserved quality of life vs fulvestrant/NSAI alone5,6

 

Time with manageable side effects

Manageable and consistent safety profile1–4,7–9

 

 

* KISQALI is not recommended to be used in combination with tamoxifen.1

PLEASE SELECT A PATIENT POPULATION AND SETTING TO FIND OUT HOW KISQALI CAN HELP WOMEN WITH HR+/HER2− aBC

 

Premenopausal women

KISQALI + non-steroidal aromatase inhibitor (NSAI) in first-line premenopausal patient population.

Show me more

Postmenopausal women

KISQALI + fulvestrant in postmenopausal patient population.

Show me more

Postmenopausal women

KISQALI + aromatase inhibitor (AI) in first-line postmenopausal patient population.

Show me more

SAFETY

Learn about KISQALI’s safety profile

 

KISQALI DOSING & MONITORING

Find out how to get started with KISQALI

 

RESOURCES

Access HCP and patient materials

 

aBC, advanced breast cancer; CDK4/6i, cyclin-dependent kinase 4 and 6 inhibitor; ET, endocrine therapy; HR+/HER2-, hormone receptor-positive/humanepidermal growth factor 2-negative; LHRH, luteinising hormone-releasing hormone; NSAI, non-steroidal aromatase inhibitor; OS, overall survival.

  1. KISQALI (ribociclib). Summary of Product Characteristics.
  2. Slamon DJ, et al. J Clin Oncol. 2018;36(24):2465–2472.
  3. Slamon DJ, et al. N Engl J Med. 2020;382(6):514–524.
  4. Im S-A, et al. N Engl J Med. 2019;381(4):307–316. 
  5. Harbeck N, et al. Ther Adv Med Oncol. 2020;12:1758835920943065.
  6. Fasching P, et al. Breast. 2020;54:148–154.
  7. Tripathy D, et al. Presentation PD2-04. Presented at San Antonio Breast Cancer Symposium 2020, 8–12 December, San Antonio, USA. 
  8. De Laurentiis M, et al. J Clin Oncol. 2020;38(15):1055–1055.
  9. De Laurentiis M, et al. J Clin Oncol. 2018;36(15):1056–1056.
  10. Finn RS, et al. Breast Cancer Res Treat. 2020;183:419–428.
  11. Goetz MP, et al. J Clin Oncol. 2017;35(32):3638–3646. 
  12. Hortobagyi GN, et al. Ann Oncol. 2018;29(7):1541–1547. 
Rate this content: 
No votes yet
UK I June 2021 I 126157
×

Ask Speakers

×

Medical Information Request

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Novartis via [email protected] or online through the pharmacovigilance intake (PVI) tool at www.report.novartis.com
If you have a question about the product, please contact Medical Information on 01276 698370 or by email at [email protected]