Nurse support during patients' first dose of MAYZENT.
About the MayzentConnect nurses
Our MayzentConnect nurse team have experience caring for a wide range of patients, including patients with MS, and have in‑depth knowledge of MAYZENT. Once MAYZENT has been prescribed, our nurse team can provide first-dose observation and ongoing monitoring.
As a precautionary measure, patients with some pre-existing cardiac conditions* should be observed in hospital for a period of 6 hours after the first dose of MAYZENT for signs and symptoms of bradycardia.
The MayzentConnect nurse will provide close monitoring, which will include:
An electrocardiogram (ECG) – taken prior to initiation and again after 6 hours. The results are sent to IQVIA Cardiac Services (ICS). A preliminary report will be sent back to the MayzentConnect nurse within 30 minutes
Blood pressure and heart rate are monitored over 6 hours
*Patients with sinus bradycardia (heart rate <55 bpm), history of first- or second-degree (Mobitz type I) atrioventricular block, history of myocardial infarction, or history of heart failure (patients with NYHA class I and II).
Indication: MAYZENT is indicated for the treatment of adult patients with SPMS with active disease evidenced by relapses or imaging features of inflammatory activity.1
ICS, IQVIA Cardiac Services; ECG, electrocardiogram; MS, multiple sclerosis; NYHA, New York Heart Association; SPMS, secondary progressive multiple sclerosis.
MAYZENT (siponimod) Summary of Product Characteristics.