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There’s a wealth of data supporting the use of Entresto in your
chronic HFrEF patients^1–7

Make Entresto your first choice, wherever your patients are in their chronic HFrEF journey^1–7

 Paradigm-hf¹  Pioneer-hf²  Transition^3,4  Prove-hf⁵  Evaluate-hf⁶

Indication: Entresto is indicated in adult patients for treatment of symptomatic chronic heart failure with reduced ejection fraction.⁷

HFrEF, heart failure with reduced ejection fraction.

References

1. McMurray JJV et al. N Engl J Med 2014; 371:993–1004.
2. Velazquez EJ et al. N Engl J Med 2019; 380:539–548.
3. Pascual-Figal D et al. ESC Heart Fail 2018; 5:327–336.
4. Wachter R et al. Eur J Heart Fail 2019; 21:998–1007.
5. Januzzi JL Jr et al. JAMA 2019; 322:1085–1095 plus supplementary info.
6. Desai AS et al. JAMA 2019; 322:1077–1084 plus supplementary info.
7. Entresto Summary of Product Characteristics, 2020.