Prescribing information



Professor Samreen Ahmed, Dr Raffaele Califano, Dr David Farrugia and CNS, Gemma Shaw review the 5-year data for dabrafenib + trametinib in NSCLC and discuss key learning from their clinical experience of this targeted combination through sharing patient case studies.

“As with the molecular non-small lung cancer paradigm, if we have an actionable mutation, I believe these patients are best served with a targeted agent, and in this case would be a combination of dabrafenib and trametinib”

Dr Raffaele Califano, The Christie and University Hospital of South Manchester

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BRAF+, v-raf murine sarcoma viral oncogene homolog B1 positive; NSCLC, non-small cell lung cancer.

Indication: Tafinlar in combination with Mekinist is indicated for the treatment of adult patients with advanced non-small cell lung cancer with a BRAF V600 mutation.1,2


  1. Tafinlar (dabrafenib) GB Summary of Product Characteristics.
  2. Mekinist (trametinib) GB Summary of Product Characteristics.
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UK | January 2022 | 167724

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